USA’s Francena McCorory and Russia’s Kseniya Ryzhova are the joint favourites over two laps of the track.
McCorory will be the only woman in Sopot to have dipped below 51 seconds this winter with 50.85 when capturing the national title at altitude in Alberqueque little more than a week ago.
Behind her, Joanna Atkins finished second in a 51.13 personal best to claim the second spot on the US team.
Ryzhova clocked 51.03 when winning the Russian title last month and, after many successes as part of Russia’s relay teams, is now looking for individual honours.
Nigeria’s Regina George, a winner in Birmingham last month, could also get among the medals, so too could hurdles specialist Kaliese Spencer of Jamaica and 19-year-old Shaunae Miller of The Bahamas.
Nicola Bamford for the IAAF